Endocrine Abstracts

Epidemiological studies have identified the intrauterine environment as a major contributor to increased rates of metabolic disease in adults, but the underlying mechanisms are poorly understood. Intrahepatic cholestasis of pregnancy (ICP) is a common liver disease of pregnancy that affects 0.5–2% pregnant women and is characterised by increased bile acid (BA) levels in the maternal serum. The influence of ICP on the metabolic health of offspring is unknown.<p class="...